Thousands of products cited by publications

IF : 13.934

2023-01-16

Hepatocyte Ninjurin2 promotes hepatic stellate cell activation and liver fibrosis through the IGF1R/EGR1/PDGF-BB signaling pathway

BackgroundLiver fibrogenesis is orchestrated by the paracrine signaling interaction between several resident cell types regulating the activation of hepatic stellate cells HSCs. However, the molecular mechanisms underlying paracrine regulation are largely unknown. The aim of this study is to elucidate the rol...

Yifan Wang , Pengyun Wang , Yubing Yu , Erwen Huang , Yufeng Yao , Di Guo , Huixin Peng , Beijia Tian , Qian Zheng , Mengru Jia , Jing Wang , Xinna Wu , Jianding Cheng , Huiying Liu , Qing K. Wang , Chengqi Xu

Source: Journal of Orthopaedic Surgery and Research

Human TNF ELISA Kit

Human IL1B ELISA Kit

Human IL6 ELISA Kit

IF :

2022-08-01

HDAC1 regulates inflammation and osteogenic differentiation of ankylosing spondylitis fibroblasts through the Wnt-Smad signaling pathway

AbstractAnkylosing spondylitis AS is a refractory autoimmune disease, whose typical pathology is the development of inflammation to ossification and ankylosis. Histone deacetylase 1 HDAC1 is considered to be a key factor involved in inflammatory gene transduction, but its role in AS remains unclear. The purpose of this...

Y Zeng, R He, Y Liu, et al.

Source: Journal of Orthopaedic Surgery and Research

Human TNF ELISA Kit

Human IL6 ELISA Kit

IF :

2022-08-01

Cord blood antimicrobial peptide LL37 levels in preterm neonates and association with preterm complications

AbstractBackgroundCathelicidinLL-37 plays a significant role in the human immune defense reaction. Preterm human immature organs being exposed to inflammation-induced injury was the critical denominator leading to the common preterm associated complications. Previous study showed LL37 concentration in preterm neonates ...

Zx Ren, Wh Mo, Ll Yang, et al.

Source: Italian Journal of Pediatrics

Human CCND1 ELISA Kit

IF :

2022-08-01

Epigenetic restoration and activation of ERβ: an inspiring approach for treatment of triple-negative breast cancer

AbstractBackgroundTriple-negative breast cancer TNBC is one of the most aggressive subtypes of breast cancer. TNBC lacks targeted therapy receptors, rendering endocrine and HER2-targeted therapies ineffective. TNBC is typically treated with cytotoxic chemotherapy followed by surgery. Targeting epigenetic modifications ...

A Salahuddin, H Ghanem, G A. Omran, et al.

Source: Medical Oncology

General TGC ELISA Kit

IF :

2022-08-01

Identification of fatty acid metabolism-related lncRNAs in the prognosis and immune microenvironment of colon adenocarcinoma

AbstractBackgroundCancer metabolism is largely altered compared to normal cells. This study aims to explore critical metabolism pathways in colon adenocarcinoma COAD, and reveal the possible mechanism of their role in cancer progression.MethodsExpression data and sequencing data of COAD samples were obtained from The C...

S Wu, Yz Gong, Jf Chen, et al.

Source: Biology Direct

Rat Tgfb1 ELISA Kit

Rat IL6 ELISA Kit

IF :

2022-08-01

Modulation of hepatic stellate cells by Mutaflor® probiotic in non-alcoholic fatty liver disease management

AbstractBackgroundNAFLD and NASH are emerging as primary causes of chronic liver disease, indicating a need for an effective treatment. Mutaflor® probiotic, a microbial treatment of interest, was effective in sustaining remission in ulcerative colitis patients.ObjectiveTo construct a genetic-epigenetic network linked t...

N M. Hany, S Eissa, M Basyouni, et al.

Source: Journal of Translational Medicine

IF :

2022-08-01

Modulation of hepatic stellate cells by Mutaflor® probiotic in non-alcoholic fatty liver disease management

N M. Hany, S Eissa, M Basyouni, et al.

Source: Journal of Translational Medicine

Rat Mtor ELISA Kit

IF :

2022-08-01

mTOR and HDAC2 are simultaneously activated during electrically induced kindling of seizures

AbstractAlthough neurotrophic pathways and epigenetic processes are believed to be significant contributors to epileptogenesis and epilepsy, therapies using modulators of these targets are still lacking. BDNF-TrkB-mTOR signalling and the RESTNRSF-coREST-HDAC2 system are critical pathways responsible for neurotrophic an...

N Chmielewska, A Wawer, B Osuch, et al.

Source: Epilepsy Research

Mouse Col1a1 ELISA Kit

IF :

2022-06-30

Small extracellular vesicles derived from dermal fibroblasts promote fibroblast activity and skin development through carrying miR-218 and ITGBL1

AbstractSkin thickness is closely related to the appearance of human skin, such as sagging and wrinkling, which primarily depends on the level of collagen I synthesized by dermal fibroblasts DFs. Small extracellular vesicles SEVs, especially those derived from human DFs HDFs, are crucial orchestrators in shaping physio...

Q Zou, M Zhang, R Yuan, et al.

Source: Journal of Nanobiotechnology

Rat Il1b ELISA Kit

IF :

2022-06-30

Different effectiveness of fungal pathogen-associated molecular patterns (PAMPs) in activating rat peritoneal mast cells

AbstractMast cells MCs are the first immune cell type that can contact with the external environment, where they may rapidly sense the presence of pathogens. These cells are directly involved in innate defense through their ability to pathogen destruction by several mechanisms and the pattern recognition receptors PRRs...

P Żelechowska, E Brzezińska-Błaszczyk, J Agier, et al.

Source: Immunology Letters

第 ◄ ► 页共 114