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ADA (基因名), Adenosine deaminase (蛋白名), ada_bovin.
产品名称:

Bovine ADA/ Adenosine deaminase ELISA Kit
腺苷脱氨

货号:

E1390b

商标:
EIAab®
监管等级:
别名:

Adenosine aminohydrolase

检测方法:
ELISA
实验类型:
Sandwich
检测范围:
3.12-200U/L
灵敏度:
1.46U/L
特异性:
Natural and recombinant bovine Adenosine deaminase
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
实验步骤:
实验步骤
研究领域:
Epigenetics
Bovine ADA ELISA Kit
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Bovine ADA ELISA Kit
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产品说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


通用注释


亚单元:
Interacts with DPP4 (via extracellular domain). Interacts with PLG (via Kringle 4 domain); the interaction stimulates PLG activation when in complex with DPP4.


功能:
Catalyzes the hydrolytic deamination of adenosine and 2-deoxyadenosine (By similarity). Plays an important role in purine metabolism and in adenosine homeostasis (By similarity). Modulates signaling by extracellular adenosine, and so contributes indirectly to cellular signaling events (By similarity). Acts as a positive regulator of T-cell coactivation, by binding DPP4 (By similarity). Its interaction with DPP4 regulates lymphocyte-epithelial cell adhesion (By similarity). Enhances dendritic cell immunogenicity by affecting dendritic cell costimulatory molecule expression and cytokines and chemokines secretion (PubMed:23240012). Enhances CD4+ T-cell differentiation and proliferation (By similarity). Acts as a positive modulator of adenosine receptors ADORA1 and ADORA2A, by enhancing their ligand affinity via conformational change (By similarity). Stimulates plasminogen activation (By similarity). Plays a role in male fertility (By similarity). Plays a protective role in early postimplantation embryonic development.


亚细胞位置:
Cell membrane Peripheral membrane protein Extracellular side Cell junction Cytoplasmic vesicle lumen Cytoplasm Lysosome Colocalized with DPP4 at the cell surface.


该产品尚未在任何出版物中被引用。
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