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FURIN (基因名), Furin (蛋白名), furin_human.
产品名称:

Human FURIN/ Furin ELISA Kit
Furin

货号:

E9700h

商标:
EIAab®
监管等级:
别名:

Dibasic-processing enzyme, Paired basic amino acid residue-cleaving enzyme, PACE, FUR, PACE, PCSK3

检测方法:
ELISA
实验类型:
Sandwich
检测范围:
0.156-10ng/mL
灵敏度:
0.049ng/mL
特异性:
Natural and recombinant human Furin
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
实验步骤:
实验步骤
研究领域:
Development Biology
Human FURIN ELISA Kit
规格 & 价格: cart
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Human FURIN ELISA Kit
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产品说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


线性
线性:给定样本通过梯度稀释,每次稀释的测量值与理论值的比值。

Sample

1:2

1:4

1:8

1:16

serum(n=5)

97-107%

90-100%

108-119%

88-98%

EDTA plasma(n=5)

104-116%

105-115%

102-111%

111-120%

heparin plasma(n=5)

101-110%

 

80-90%

103-112%

107-117%

 

通用注释


亚单元:
Interacts with FLNA (By similarity). Binds to PACS1 which mediates TGN localization and connection to clathrin adapters (PubMed:11331585).


功能:
(Microbial infection) Probaly cleaves and activates anthrax and diphtheria toxins. Required for H7N1 and H5N1 influenza virus infection probably by cleaving hemagglutinin.


亚细胞位置:
Golgi apparatus Trans-Golgi network membrane Single-pass type I membrane protein Cell membrane Single-pass type I membrane protein Secreted Endosome membrane Single-pass type I membrane protein Shuttles between the trans-Golgi network and the cell surface (PubMed:9412467, PubMed:11799113). Propeptide cleavage is a prerequisite for exit of furin molecules out of the endoplasmic reticulum (ER). A second cleavage within the propeptide occurs in the trans Golgi network (TGN), followed by the release of the propeptide and the activation of furin (PubMed:11799113).


该产品尚未在任何出版物中被引用。
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