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IDO1 (基因名), Indoleamine 2,3-dioxygenase 1 (蛋白名), i23o1_human.
产品名称:

IDO1 Antibody

货号:

P1547Rb-h

商标:
EIAab®
监管等级:
别名:

Indoleamine-pyrrole 2, 3-dioxygenase, IDO-1, IDO, INDO

序列号:
P14902
反应性:
human
免疫原:
corresponding to a sequence mapping at the 1-240aa of P14902
形态:
Liquid
存储说明:
4℃ for frequent use, -20℃ to -70℃ for 6 months
缓冲液:
0.1M×PBS,50% glycerol,pH7.5
浓度:
200ug/ml
纯化方式:
Immunogen affinity purified
克隆性:
Polyclonal
亚型:
Rabbit IgG
应用:
推荐产品:
研究领域:
Cell Biology
Human IDO1 Polyclonal Antibody
规格 & 价格: cart
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Human IDO1 Polyclonal Antibody
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产品说明书
数据表: 下载说明书
MSDS: MSDS
在线询价


R&D 技术数据
Immunohistochemical analysis of paraffin-embedded Human kidney using IDO1 antibody.
通用注释


亚单元:
Monomer.


功能:
Catalyzes the first and rate limiting step of the catabolism of the essential amino acid tryptophan along the kynurenine pathway (PubMed:17671174). Involved in the peripheral immune tolerance, contributing to maintain homeostasis by preventing autoimmunity or immunopathology that would result from uncontrolled and overreacting immune responses (PubMed:25691885). Tryptophan shortage inhibits T lymphocytes division and accumulation of tryptophan catabolites induces T-cell apoptosis and differentiation of regulatory T-cells (PubMed:25691885). Acts as a suppressor of anti-tumor immunity (PubMed:23103127, PubMed:25157255, PubMed:14502282, PubMed:25691885). Limits the growth of intracellular pathogens by depriving tryptophan (PubMed:25691885). Protects the fetus from maternal immune rejection (PubMed:25691885).


亚细胞位置:
Cytoplasm Cytosol


该产品尚未在任何出版物中被引用。
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