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OAS2 (基因名), 2'-5'-oligoadenylate synthase 2 (蛋白名), oas2_human.
产品名称:

OAS2 Antibody

货号:

P0722Rb

商标:
EIAab®
监管等级:
别名:

p69 OAS / p71 OAS, p69OAS / p71OAS, (2-5')oligo(A) synthase 2

序列号:
P29728
反应性:
human, mouse
免疫原:
Recombinant human OAS2 protein ( R0722h )
形态:
Liquid
存储说明:
4℃ for frequent use, -20℃ to -70℃ for 6 months
缓冲液:
0.1M×PBS,50% glycerol,pH7.5
浓度:
200ug/ml
纯化方式:
Immunogen affinity purified
克隆性:
Polyclonal
亚型:
Rabbit IgG
推荐产品:
研究领域:
Immunology
Human OAS2 Polyclonal Antibody
规格 & 价格: cart
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Human OAS2 Polyclonal Antibody
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产品说明书
数据表: 下载说明书
MSDS: MSDS
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通用注释


亚单元:
Homodimer.


功能:
Interferon-induced, dsRNA-activated antiviral enzyme which plays a critical role in cellular innate antiviral response. In addition, it may also play a role in other cellular processes such as apoptosis, cell growth, differentiation and gene regulation. Synthesizes higher oligomers of 2'-5'-oligoadenylates (2-5A) from ATP which then bind to the inactive monomeric form of ribonuclease L (RNase L) leading to its dimerization and subsequent activation. Activation of RNase L leads to degradation of cellular as well as viral RNA, resulting in the inhibition of protein synthesis, thus terminating viral replication. Can mediate the antiviral effect via the classical RNase L-dependent pathway or an alternative antiviral pathway independent of RNase L.


亚细胞位置:
Cytoplasm Cytoplasm Perinuclear region Mitochondrion Nucleus Microsome Endoplasmic reticulum Associated with different subcellular fractions such as mitochondrial, nuclear, and rough/smooth microsomal fractions.


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