Apaf1 (基因名), Apoptotic protease-activating factor 1 (蛋白名), apaf_rat.
产品名称:
Rat Apaf1/ Apoptotic protease-activating factor 1 CLIA Kit
凋亡蛋白酶激活因子1
货号:
U1054r
商标:
EIAab®
监管等级:
别名:
APAF-1
检测方法:
CLIA
实验类型:
Sandwich
检测范围:
39-2500pg/mL
特异性:
Natural and recombinant rat Apoptotic protease-activating factor 1
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
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研究领域:
Neurosciences
通用注释
亚单元:
Monomer. Oligomerizes to a heptameric ring, known as the apoptosome, upon binding of cytochrome c and dATP. Oligomeric Apaf-1 and pro-caspase-9 bind to each other via their respective NH2-terminal CARD domains. Interacts with UACA. Interacts with APIP (By similarity). Interacts (via CARD and NACHT domains) with NAIP/BIRC1 (via NACHT domain).
功能:
Regulates progammed cell death; necessary for normal brain development. Participates with pro-caspase-9 (Apaf-3) in the cytochrome c-dependent activation of caspase-3, leading to apoptosis. This activation requires ATP.
亚细胞位置:
Cytoplasm
验证序列:
反馈墙
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