EGF (基因名), Pro-epidermal growth factor (蛋白名), egf_human.
产品名称:
Human EGF/ Pro-epidermal growth factor CLIA Kit
表皮生长因子
货号:
U0560h
商标:
EIAab®
监管等级:
别名:
EGF
检测方法:
CLIA
实验类型:
Sandwich
检测范围:
1.95-125pg/mL
特异性:
Natural and recombinant human Pro-epidermal growth factor
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
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研究领域:
Cancer
通用注释
亚单元:
Interacts with EGFR and promotes EGFR dimerization. Interacts with RHBDF2 (By similarity). Interacts with RHBDF1; may retain EGF in the endoplasmic reticulum and regulates its degradation through the endoplasmic reticulum-associated degradation (ERAD).
功能:
EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. Can induce neurite outgrowth in motoneurons of the pond snail Lymnaea stagnalis in vitro (PubMed:10964941).
亚细胞位置:
Membrane
Single-pass type I membrane protein
[1].
Meixia Zhang, Xiaolei Shan, Li Guv, Leif Hertz and Liang Peng
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