FBLN1 (基因名), Fibulin-1 (蛋白名), fbln1_human.
产品名称:
Human FBLN1/ Fibulin-1 CLIA Kit
衰老关键蛋白1
货号:
U0136h
商标:
EIAab®
监管等级:
别名:
PP213, FIBL-1
检测方法:
CLIA
实验类型:
Sandwich
检测范围:
62.5-4000pg/mL
特异性:
Natural and recombinant human Fibulin-1
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
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研究领域:
Immunology
通用注释
亚单元:
Homomultimerizes and interacts with various extracellular matrix components such as FN1, LAMA1, LAMA2, NID, ACAN, CSPG2 and type IV collagen. Interacts also with APP, NOV, FGB and HPV type 16, HPV type 18, HPV type 31 and BPV type 1 E6 proteins. Interacts with FBLN7.
功能:
Incorporated into fibronectin-containing matrix fibers. May play a role in cell adhesion and migration along protein fibers within the extracellular matrix (ECM). Could be important for certain developmental processes and contribute to the supramolecular organization of ECM architecture, in particular to those of basement membranes. Has been implicated in a role in cellular transformation and tumor invasion, it appears to be a tumor suppressor. May play a role in haemostasis and thrombosis owing to its ability to bind fibrinogen and incorporate into clots. Could play a significant role in modulating the neurotrophic activities of APP, particularly soluble APP.
亚细胞位置:
Secreted
Extracellular space
Extracellular matrix
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