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IL23A (基因名), Interleukin-23 subunit alpha (蛋白名), il23a_human.

产品名称:

IL23A Antibody
白介素23α亚基

货号:

M0384Rb-h

商标:

EIAab^®

监管等级:

RUO

别名:

Interleukin-23 subunit p19, IL-23p19, UNQ2498/PRO5798, IL-23 subunit alpha, SGRF

反应性:

human

免疫原:

corresponding to a sequence mapping at the 58-142aa of Q9NPF7

形态:

Liquid

存储说明:

4℃ for frequent use, -20℃ to -70℃ for 6 months

缓冲液:

0.1M×PBS,50% glycerol,pH7.5

浓度:

200ug/ml

纯化方式:

Immunogen affinity purified

克隆性:

Monoclonal

亚型:

Mouse IgG

应用:

推荐产品:

Goat Anti-Mouse IgG(H+L) HRP-conjugated Antibody

研究领域:

Immunology

规格 & 价格:

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Human IL23A Monoclonal Antibody

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R&D 技术数据

更多信息，请参阅手册，或联系我们的技术支持: tech@eiaab.com.

通用注释

亚单元:

Heterodimer with IL12B; disulfide-linked. The heterodimer is known as interleukin IL-23.

功能:

Associates with IL12B to form the IL-23 interleukin, a heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 may constitute with IL-17 an acute response to infection in peripheral tissues. IL-23 binds to a heterodimeric receptor complex composed of IL12RB1 and IL23R, activates the Jak-Stat signaling cascade, stimulates memory rather than naive T-cells and promotes production of proinflammatory cytokines. IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tumorigenesis.

亚细胞位置:

Secreted Secreted upon association with IL12B.

数据库链接

UniGene:

Hs.382212

SMR:

Q9NPF7

STRING:

9606.ENSP00000228534

KEGG:

hsa:51561

MIM: