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ABCA1 (基因名), Phospholipid-transporting ATPase ABCA1 (蛋白名), abca1_human.
产品名称:

ABCA1 Antibody

货号:

P1242Rb-h

商标:
EIAab®
监管等级:
别名:

ATP-binding cassette sub-family A member 1, ATP-binding cassette transporter 1, Cholesterol efflux regulatory protein, ABC-1, ABC1, CERP

序列号:
O95477
反应性:
human
免疫原:
corresponding to a sequence mapping at the Recombinant Protein of O95477
形态:
Liquid
存储说明:
4℃ for frequent use, -20℃ to -70℃ for 6 months
缓冲液:
0.1M×PBS,50% glycerol,pH7.5
浓度:
200ug/ml
纯化方式:
Immunogen affinity purified
克隆性:
Polyclonal
亚型:
Rabbit IgG
应用:
推荐产品:
研究领域:
Cardiovascular
  • Human ABCA1 Polyclonal Antibody
  • Human ABCA1 Polyclonal Antibody
  • Human ABCA1 Polyclonal Antibody
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Human ABCA1 Polyclonal Antibody
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产品说明书
数据表: 下载说明书
MSDS: MSDS


R&D 技术数据
Human ABCA1 Polyclonal Antibody
Mouse peritoneal proteinwas subjected to SDS-PAGE followed by Western Blot with ATP-binding cassette sub-family A member 1antibody at dilution of 1:300
Detection of ABCA1 in prostate epithelium showing luminal and membrane staining using ABCA1 antibody.[antibody dilution: 1:200]
通用注释


亚单元:
Interacts with MEGF10 (PubMed:17205124). May interact with APOE1; functionally associated with APOE1 in the biogenesis of HDLs (PubMed:14754908).


功能:
Catalyzes the translocation of specific phospholipids from the cytoplasmic to the extracellular/lumenal leaflet of membrane coupled to the hydrolysis of ATP (PubMed:24097981). Thereby, participates to phospholipids transfer to apoliproteins to form nascent high density lipoproteins/HDLs (PubMed:14754908). Transports preferentially phosphatidylcholine over phosphatidylserine (PubMed:24097981). May involved indirectly in the efflux of intracellular cholesterol and its transfer to apoliproteins to form nascent high density lipoproteins/HDLs (PubMed:10533863, PubMed:14754908, PubMed:24097981).


亚细胞位置:
Membrane Multi-pass membrane protein Cell membrane Endosome


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