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ASPRO (短名 ),
产品名称:

ASPRO Antibody

货号:

P15190Rb

商标:
EIAab®
监管等级:
序列号:
P35555
反应性:
human,mouse
免疫原:
Recombinant human FBN1 Protein (R15190h)
形态:
Liquid
存储说明:
4℃ for frequent use, -20℃ to -70℃ for 6 months
缓冲液:
0.1M×PBS,50% glycerol,pH7.5
浓度:
200ug/ml
纯化方式:
Immunogen affinity purified
克隆性:
Polyclonal
亚型:
Rabbit IgG
应用:
推荐产品:
研究领域:
-
Human ASPRO Polyclonal Antibody
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Human ASPRO Polyclonal Antibody
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产品说明书
数据表: 下载说明书
MSDS: MSDS
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通用注释


亚单元:
Asprosin, a fasting-induced glucogenic protein homone that modulates hepatic glucose release. It is the C-terminal cleavage product of profibrillin, and encoded by the ultimate two exons of FBN1.


功能:
Circulating asprosin, a protein hormone, responds to low dietary glucose by triggering the release of liver glucose stores, and the reduction of asprosin protects against the hyperinsulinism associated with metabolic syndrome.


Location:
Asprosin circulates at nanomolar levels, a single dose of recombinant asprosin retains biological activity and elevates blood glucose and insulin levels. Liver is the target organ for asprosin to recruit. Asprosin increases hepatocyte glucose release through activating the G protein-cAMP-PKA pathway.



[5].
R Janoschek, T Hoffmann, G Sengle, et al.
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