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ALCAM (基因名), CD166 antigen (蛋白名), cd166_human.
产品名称:

ALCAM Antibody

货号:

P0002Rb-h

商标:
EIAab®
监管等级:
别名:

Activated leukocyte cell adhesion molecule, CD166, MEMD

序列号:
Q13740
反应性:
human
免疫原:
Recombinant human ALCAM protein ( R0002h )
形态:
Liquid
存储说明:
4℃ for frequent use, -20℃ to -70℃ for 6 months
缓冲液:
0.1M×PBS,50% glycerol,pH7.5
浓度:
200ug/ml
纯化方式:
Immunogen affinity purified
克隆性:
Polyclonal
亚型:
Rabbit IgG
应用:
推荐产品:
研究领域:
-
Human ALCAM Polyclonal Antibody
规格 & 价格: cart
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Human ALCAM Polyclonal Antibody
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产品说明书
数据表: 下载说明书
MSDS: MSDS
在线询价


R&D 技术数据
HC of paraffin-embedded cervical cancer tissues using ALCAM antibody with DAB staining.[antibody concentration 3 ug/ml]
通用注释


亚单元:
Homodimer (PubMed:7760007, PubMed:16352806, PubMed:15048703, PubMed:26146185). Interacts (via extracellular domain) with CD6 (via extracellular domain) (PubMed:7760007, PubMed:8823162, PubMed:15048703, PubMed:16914752, PubMed:24945728, PubMed:26146185). Homodimerization and interaction with CD6 involve the same region and cannot occur simultaneously. The affinity for CD6 is much higher than the affinity for self-association (PubMed:15048703). Interacts (via glycosylated extracellular domain) with LGALS1 and LGALS3 (PubMed:24945728). Interaction with LGALS1 or LGALS3 inhibits interaction with CD6 (PubMed:24945728).


功能:
Isoform 3: Inhibits activities of membrane-bound isoforms by competing for the same interaction partners. Inhibits cell attachment via homotypic interactions. Promotes endothelial cell migration. Inhibits endothelial cell tube formation.


亚细胞位置:
Isoform 3 Secreted


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