首页 > 一抗 > TIMP1 Antibody

TIMP1 (基因名), Metalloproteinase inhibitor 1 (蛋白名), timp1_human.

产品名称:

TIMP1 Antibody

货号:

P0552Rb-h

商标:

EIAab^®

监管等级:

RUO

别名:

Erythroid-potentiating activity, Fibroblast collagenase inhibitor, Tissue inhibitor of metalloproteinases 1, EPA, Collagenase inhibitor, TIMP-1, CLGI, TIMP

序列号:

P01033

反应性:

human

免疫原:

corresponding to a sequence mapping at the 24-207aa of P01033

形态:

Liquid

存储说明:

4℃ for frequent use, -20℃ to -70℃ for 6 months

缓冲液:

0.1M×PBS,50% glycerol,pH7.5

浓度:

200ug/ml

纯化方式:

Immunogen affinity purified

克隆性:

Polyclonal

亚型:

Rabbit IgG

应用:

推荐产品:

Goat Anti-Rabbit IgG(H+L) HRP-conjugated Antibody

研究领域:

Cardiovascular

规格 & 价格:

关注

Human TIMP1 Polyclonal Antibody

邮箱 *

消息 *

Please 登录.

产品说明书

数据表:

MSDS:

在线询价

数据
文献 ( 1 )
序列 / 3D
常见问题解答
反馈墙 (0)

R&D 技术数据

Immunohistochemical analysis of formalin-fixed paraffin embedded human pancreas tissue using TIMP1 antibody.

通用注释

亚单元:

Interacts with MMP1, MMP3, MMP10 and MMP13, but has only very low affinity for MMP14. Interacts with CD63; identified in a complex with CD63 and ITGB1.

功能:

Metalloproteinase inhibitor that functions by forming one to one complexes with target metalloproteinases, such as collagenases, and irreversibly inactivates them by binding to their catalytic zinc cofactor. Acts on MMP1, MMP2, MMP3, MMP7, MMP8, MMP9, MMP10, MMP11, MMP12, MMP13 and MMP16. Does not act on MMP14. Also functions as a growth factor that regulates cell differentiation, migration and cell death and activates cellular signaling cascades via CD63 and ITGB1. Plays a role in integrin signaling. Mediates erythropoiesis in vitro; but, unlike IL3, it is species-specific, stimulating the growth and differentiation of only human and murine erythroid progenitors.

亚细胞位置:

Secreted

数据库链接

UniGene:

Hs.522632

SMR:

P01033

STRING:

9606.ENSP00000218388

KEGG:

hsa:7076

MIM: