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TNFRSF11B (基因名), Tumor necrosis factor receptor superfamily member 11B (蛋白名), tr11b_human.
产品名称:

TNFRSF11B Antibody

货号:

P0108Rb-h

商标:
EIAab®
监管等级:
别名:

Osteoclastogenesis inhibitory factor, Osteoprotegerin, OCIF, OPG

序列号:
O00300
反应性:
human
免疫原:
corresponding to a sequence mapping at the 22-401aa of O00300
形态:
Liquid
存储说明:
4℃ for frequent use, -20℃ to -70℃ for 6 months
缓冲液:
0.1M×PBS,50% glycerol,pH7.5
浓度:
200ug/ml
纯化方式:
Immunogen affinity purified
克隆性:
Polyclonal
亚型:
Rabbit IgG
应用:
推荐产品:
研究领域:
Immunology
Human TNFRSF11B Polyclonal Antibody
规格 & 价格: cart
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Human TNFRSF11B Polyclonal Antibody
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产品说明书
数据表: 下载说明书
MSDS: MSDS
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R&D 技术数据
Immunohistochemical analysis of formalin fixed and paraffin embedded rat tibia tissue using TNFRSF11B antibody.
通用注释


亚单元:
Homodimer. Interacts with TNFSF10 and TNFSF11.


功能:
Acts as decoy receptor for TNFSF11/RANKL and thereby neutralizes its function in osteoclastogenesis. Inhibits the activation of osteoclasts and promotes osteoclast apoptosis in vitro. Bone homeostasis seems to depend on the local ratio between TNFSF11 and TNFRSF11B. May also play a role in preventing arterial calcification. May act as decoy receptor for TNFSF10/TRAIL and protect against apoptosis. TNFSF10/TRAIL binding blocks the inhibition of osteoclastogenesis.


亚细胞位置:
Secreted


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