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NPPB (基因名), Natriuretic peptides B (蛋白名), anfb_human.
产品名称:

Human NPPB/ Natriuretic peptides B Recombinant Protein
脑钠素/脑钠尿肽

货号:

R0541h

商标:
EIAab®
监管等级:
别名:

Gamma-brain natriuretic peptide, BNP

序列号:
P16860
来源:
E.coli
种属:
Human
标签:
His
序列:
27-134aa
预估分子量:
11.88 kDa (monomer)
纯度:
Greater than 90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
-
  • Human NPPB Protein
  • Human NPPB Protein
  • Human NPPB Protein
规格 & 价格: cart
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Human NPPB Protein
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产品说明书
数据表: 下载说明书
MSDS: MSDS
在线询价


R&D 技术数据
Human NPPB Protein
The PCR product of human NPPB gene was determined by 1% Agarose stained with EB.
Human NPPB Protein
Recombinant human NPPB protein was determined by 12% SDS-PAGE stained with Coomassie Blue under reducing conditions.
基因位点
Cytogenetic band: 1p36.22 by HGNC 1p36.22 by Entrez Gene 1p36.22 by Ensembl
NPPB Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
N/A


功能:
Cardiac hormone which may function as a paracrine antifibrotic factor in the heart. Also plays a key role in cardiovascular homeostasis through natriuresis, diuresis, vasorelaxation, and inhibition of renin and aldosterone secretion. Specifically binds and stimulates the cGMP production of the NPR1 receptor. Binds the clearance receptor NPR3.


亚细胞位置:
Secreted



[1].
"Dysfunctional corin i555(p568) allele is associated with impaired brain natriuretic peptide processing and adverse outcomes in blacks with systolic heart failure: results from the Genetic Risk Assessment in Heart Failure substudy."

[2].
"Association between the T-381C polymorphism of the brain natriuretic peptide gene and risk of type 2 diabetes in human populations."

[3].
"A novel variable number of tandem repeat of the natriuretic peptide precursor B gene's 5'-flanking region is associated with essential hypertension among Japanese females."

[4].
"Mutation analysis of the natriuretic peptide precursor B (NPPB) gene in patients with hypertrophic cardiomyopathy."

[5].
"Association of the -381T/C promoter variation of the brain natriuretic peptide gene with low bone-mineral density and rapid postmenopausal bone loss."
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