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CTSG (基因名), Cathepsin G (蛋白名), catg_human.
产品名称:

Human CTSG/ Cathepsin G Recombinant Protein
组织蛋白酶G

货号:

R1730h

商标:
EIAab®
监管等级:
别名:

CG

序列号:
P08311
来源:
E.coli
种属:
Human
标签:
His
序列:
19-255aa
预估分子量:
26.07 kDa (monomer)
纯度:
Greater than 95% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
Signal Transduction
  • Human CTSG Protein
  • Human CTSG Protein
  • Human CTSG Protein
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Human CTSG Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


R&D 技术数据
Human CTSG Protein
The PCR product of human CTSG gene was determined by 1% Agarose stained with EB.
Human CTSG Protein
Recombinant human CTSG protein was determined by 12% SDS-PAGE stained with Coomassie Blue under reducing conditions.
基因位点
Cytogenetic band: 14q12 by HGNC 14q12 by Entrez Gene 14q12 by Ensembl
CTSG Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
(Microbial infection) Interacts with M.tuberculosis protein Rv3364c.


功能:
Serine protease with trypsin- and chymotrypsin-like specificity. Cleaves complement C3. Has antibacterial activity against the Gram-negative bacterium P.aeruginosa, antibacterial activity is inhibited by LPS from P.aeruginosa, Z-Gly-Leu-Phe-CH2Cl and phenylmethylsulfonyl fluoride.


亚细胞位置:
Cell surface



[1].
"The 1.8 A crystal structure of human cathepsin G in complex with Suc-Val-Pro-PheP-(OPh)2: a Janus-faced proteinase with two opposite specificities."

[2].
"Comparison of granule proteins from human polymorphonuclear leukocytes which are bactericidal toward Pseudomonas aeruginosa."

[3].
"Genomic organization and chromosomal localization of the human cathepsin G gene."

[4].
"Polymorphisms in innate immunity genes and patients response to dendritic cell-based HIV immuno-treatment."

[5].
"Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study."

[6].
"Investigation of genetic susceptibility factors for human longevity - a targeted nonsynonymous SNP study."

[7].
"Cathepsin G: roles in antigen presentation and beyond."

[8].
"Association of a polymorphism of the apolipoprotein E gene with chronic kidney disease in Japanese individuals with metabolic syndrome."

[9].
"Co-localization of tryptase and cathepsin-G in mast cells in cutaneous mastocytosis."

[10].
"Association of genetic variants with chronic kidney disease in individuals with different lipid profiles."
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