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EGF (基因名), Pro-epidermal growth factor (蛋白名), egf_human.
产品名称:

Human EGF/ Pro-epidermal growth factor Recombinant Protein
表皮生长因子

货号:

R0560h

商标:
EIAab®
监管等级:
别名:

EGF

序列号:
P01133
来源:
E.coli
种属:
Human
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
Cancer
Human EGF Protein
规格 & 价格: cart
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Human EGF Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
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R&D 技术数据
更多信息,请参阅手册,或联系我们的技术支持: tech@eiaab.com.
基因位点
Cytogenetic band: 4q25 by HGNC 4q25 by Entrez Gene 4q25 by Ensembl
EGF Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
Interacts with EGFR and promotes EGFR dimerization. Interacts with RHBDF2 (By similarity). Interacts with RHBDF1; may retain EGF in the endoplasmic reticulum and regulates its degradation through the endoplasmic reticulum-associated degradation (ERAD).


功能:
EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. Can induce neurite outgrowth in motoneurons of the pond snail Lymnaea stagnalis in vitro (PubMed:10964941).


亚细胞位置:
Membrane Single-pass type I membrane protein



[1].
"EGF promoter SNPs, plasma EGF levels and risk of breast cancer in Chinese women."

[2].
"Genetic susceptibility of epidermal growth factor +61A>G and transforming growth factor beta1 -509C>T gene polymorphisms with gallbladder cancer."

[3].
"A functional epidermal growth factor (EGF) polymorphism, EGF serum levels, and esophageal adenocarcinoma risk and outcome."

[4].
"Polymorphisms in angiogenesis-related genes and prostate cancer."

[5].
"Epidermal growth factor gene functional polymorphism and the risk of hepatocellular carcinoma in patients with cirrhosis."
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