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PLA2G7 (基因名), Platelet-activating factor acetylhydrolase (蛋白名), pafa_human.
产品名称:

Human PLA2G7/ Platelet-activating factor acetylhydrolase Recombinant Protein
血小板活化因子乙酰水解

货号:

R0867h

商标:
EIAab®
监管等级:
别名:

1-alkyl-2-acetylglycerophosphocholine esterase, 2-acetyl-1-alkylglycerophosphocholine esterase, Group-VIIA phospholipase A2, LDL-associated phospholipase A2, PAF 2-acylhydrolase, gVIIA-PLA2, LDL-PLA(2), PAF acetylhydrolase, PAFAH

序列号:
Q13093
来源:
E.coli
种属:
Human
标签:
His
序列:
181-289aa
预估分子量:
11.99 kDa (monomer)
纯度:
Greater than 98% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
Immunology
  • Human PLA2G7 Protein
  • Human PLA2G7 Protein
  • Human PLA2G7 Protein
规格 & 价格: cart
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Human PLA2G7 Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


R&D 技术数据
The sequence analysis of human PLA2G7 protein including hydrophilcity, hydrophobicity and antigenicity.
Human PLA2G7 Protein
Recombinant human PLA2G7 protein was determined by 12% SDS-PAGE stained with Coomassie Blue under reducing conditions.
基因位点
Cytogenetic band: 6p12.3 by HGNC 6p12.3 by Entrez Gene 6p12.3 by Ensembl
PLA2G7 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
N/A


功能:
Modulates the action of platelet-activating factor (PAF) by hydrolyzing the sn-2 ester bond to yield the biologically inactive lyso-PAF. Has a specificity for substrates with a short residue at the sn-2 position. It is inactive against long-chain phospholipids.


亚细胞位置:
Secreted Extracellular space



[1].
"Purification, properties, sequencing, and cloning of a lipoprotein-associated, serine-dependent phospholipase involved in the oxidative modification of low-density lipoproteins."

[2].
"Identification of the G994T polymorphism in exon 9 of plasma platelet-activating factor acetylhydrolase gene as a risk factor for polycystic ovary syndrome."

[3].
"Inter-individual variability of plasma PAF-acetylhydrolase activity in ARDS patients and PAFAH genotype."

[4].
"Comprehensive genetic analysis of the platelet activating factor acetylhydrolase (PLA2G7) gene and cardiovascular disease in case-control and family datasets."

[5].
"Crystal structure of human plasma platelet-activating factor acetylhydrolase: structural implication to lipoprotein binding and catalysis."
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