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MPO (基因名), Myeloperoxidase (蛋白名), perm_human.

产品名称:

Human MPO/ Myeloperoxidase Recombinant Protein
髓过氧化物

货号:

R0601h

商标:

EIAab^®

监管等级:

RUO

别名:

MPO

序列号:

P05164

来源:

E.coli

种属:

Human

标签:

His

序列:

591-745aa

预估分子量:

17.05 kDa (monomer)

纯度:

Greater than 95% by SDS-PAGE

浓度:

Reconstitution Dependent

形态:

Liquid

内毒素水平:

Please contact protein@eiaab.com The technician for more information.

应用:

存储缓冲液:

50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)

存储:

Store at -20°C. (Avoid repeated freezing and thawing.)

研究领域:

Immunology

规格 & 价格:

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Human MPO Protein

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产品说明书

数据表:

MSDS:

在线询价

数据
文献 ( 2 )
出版物
序列 / 3D
视频
常见问题解答
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R&D 技术数据

The PCR product of human MPO gene was determined by 1% Agarose stained with EB.

Recombinant human MPO protein was determined by 12% SDS-PAGE stained with Coomassie Blue under reducing conditions.

基因位点

Cytogenetic band: 17q22 by HGNC 17q22 by Entrez Gene 17q22 by Ensembl

MPO Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)

通用注释

亚单元:

Homodimer; disulfide-linked. Each monomer consists of a light and a heavy chain.

功能:

Part of the host defense system of polymorphonuclear leukocytes. It is responsible for microbicidal activity against a wide range of organisms. In the stimulated PMN, MPO catalyzes the production of hypohalous acids, primarily hypochlorous acid in physiologic situations, and other toxic intermediates that greatly enhance PMN microbicidal activity.

亚细胞位置:

Lysosome

数据库链接

UniGene:

Hs.458272

SMR:

P05164

STRING:

9606.ENSP00000225275

KEGG:

hsa:4353

MIM:

254600

Pfam:

PF03098

Uniprot:

P05164

相关产品

序列长度:

745

序列:

仅供参考，详细请咨询（services@eiaab.com）

50:

100:

150:

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250:

300:

350:

400:

450:

500:

550:

600:

650:

700:

745:

RIICDNTGIT | TVSKNNIFMS | NSYPRDFVNC | STLPALNLAS | WREAS

3D 模型:

3D 结构:

免疫原序列:

验证序列:

[1].

"Explosive type of moderate-resistance training induces functional, cardiovascular, and molecular adaptations in the elderly"

MRB Valls, I Dimauro, A Brunelli, et al.

From: Age

[2].

"Resistance training and redox homeostasis: Correlation with age-associated genomic changes"

Ivan D, Mattia S, Cristina F, et al.

From: Redox Biology

[1].

"Association between myeloperoxidase polymorphisms and its plasma levels with severity of coronary artery disease."

(PMID: 19651119)

[2].

"No relationship between neutrophil granulocyte activation and the myeloperoxidase gene - 129 G>A and - 463 G>A promoter polymorphisms: implications for investigations of cardiovascular disease."

(PMID: 19877306)

[3].

"Myeloperoxidase genotypes and enhanced efficacy of chemotherapy for early-stage breast cancer in SWOG-8897."

(PMID: 19752340)

[4].

"A myeloperoxidase promoter polymorphism is independently associated with mortality in patients with impaired left ventricular function."

(PMID: 19735726)

[5].

"A prospective study of genetic polymorphism in MPO, antioxidant status, and breast cancer risk."

(PMID: 18340529)

[6].

"Myeloperoxidase and superoxide dismutase 2 polymorphisms comodulate the risk of hepatocellular carcinoma and death in alcoholic cirrhosis."

(PMID: 19731237)

[7].

"Melatonin is a potent inhibitor for myeloperoxidase."

(PMID: 18237195)

[8].

"Myeloperoxidase and superoxide dismutase polymorphisms are associated with an increased risk of developing pancreatic adenocarcinoma."

(PMID: 18205184)

[9].

"Genetic polymorphisms in the oxidative stress pathway and susceptibility to non-Hodgkin lymphoma."

(PMID: 17149600)

[10].

"Relationships between polymorphisms in NOS3 and MPO genes, cigarette smoking and risk of post-menopausal breast cancer."

(PMID: 17259657)

[1].

人髓过氧化物(MPO)重组蛋白是否是无菌的？

蛋白试剂瓶和蛋白保存液是经过高压灭菌的，但也不能保证蛋白是完全无菌的。如果要求蛋白是无菌的，可以用0.2微米的滤器对蛋白进行过滤。

[2].

人髓过氧化物(MPO)重组蛋白的保存缓冲液是什么？

纯化后的蛋白保存在PBS（58mM Na2HPO4, 17mM NaH2PO4, 68mM NaCl, pH7.4）里，并往里面加入500mM咪唑和10%甘油。

[3].

怎样确定人髓过氧化物(MPO)重组蛋白的浓度？

蛋白浓度的确定没有一个统一的标准，这主要取决于蛋白的氨基酸序列。伊艾博是根据不同测试的组合来测定蛋白浓度。考马斯亮蓝法、BCA法、氨基酸序列和氨基酸全序列分析法等都用来测定蛋白浓度。

[4].

人髓过氧化物(MPO)重组蛋白蛋白保存条件是怎样的？

蛋白应保存在 -20℃或 -80℃条件下，为了避免反复冻融，可以将蛋白分装成小份保存。

[5].

人髓过氧化物(MPO)重组蛋白是否可以用于活体实验？

重组蛋白没有用于任何的活体实验，因此蛋白的活性和半衰期是不确定的。

[6].

人髓过氧化物(MPO)重组蛋白的保质期是多久？

在适当的保存条件下，从购买之日起蛋白可以稳定保存6-12个月。适当的保存条件是:蛋白保存在-20°C o或 -80℃，保证蛋白的保存浓度高于0.1mg/ml，限制蛋白反复冻融的次数。我们公司常规的质量检测保证所有产品在销售时都有可接受的生物活性。但是我们不能控制终端用户蛋白的保存条件。如果产品在有效期内出现问题，请联系我们的技术支持。

[7].

你们蛋白和抗体的报价是怎么样的？

我们将根据你需要的蛋白和抗体的大小进行报价。

[8].

人髓过氧化物(MPO)重组蛋白是否能够提供蛋白片段？

我们现有的人的蛋白的序列可以有很多。你可以选择你感兴趣的靶向部分，我们将会按您的需求提供蛋白和抗体。

[9].

人髓过氧化物(MPO)重组蛋白的货期或发货时间一般是多长？

具体指标的货期需要确定。最快一周，最长可能一个月。

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Human MPO/ Myeloperoxidase Recombinant Protein髓过氧化物

R0601h

MPO

Human MPO/ Myeloperoxidase Recombinant Protein
髓过氧化物