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SERPINA12 (基因名), Serpin A12 (蛋白名), spa12_human.
产品名称:

Human SERPINA12/ Serpin A12 Recombinant Protein
SerpinA12

货号:

R0706h

商标:
EIAab®
监管等级:
别名:

OL-64, Visceral adipose tissue-derived serine protease inhibitor, Visceral adipose-specific serpin, Vaspin

序列号:
Q8IW75
来源:
E.coli
种属:
Human
标签:
His
序列:
21-414aa
预估分子量:
43.34 kDa (monomer)
纯度:
Greater than 98% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
-
Human SERPINA12 Protein
规格 & 价格: cart
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Human SERPINA12 Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
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R&D 技术数据
更多信息,请参阅手册,或联系我们的技术支持: tech@eiaab.com.
基因位点
Cytogenetic band: 14q32.13 by HGNC 14q32.13 by Entrez Gene 14q32.13 by Ensembl
SERPINA12 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
Forms a stable complex with KLK7.


功能:
Adipokine that modulates insulin action by specifically inhibiting its target protease KLK7 in white adipose tissues.


亚细胞位置:
Secreted



[1].
"Vaspin (SERPINA12) genotypes and risk of type 2 diabetes: Results from the MONICA/KORA studies."

[2].
"Visceral adipose tissue-derived serine protease inhibitor: a unique insulin-sensitizing adipocytokine in obesity."

[3].
"Glycosylation of human vaspin (SERPINA12) and its impact on serpin activity, heparin binding and thermal stability."

[4].
"A unique serpin P1' glutamate and a conserved β-sheet C arginine are key residues for activity, protease recognition and stability of serpinA12 (vaspin)."

[5].
"Update of the human and mouse SERPIN gene superfamily."

[6].
"Vaspin inhibits kallikrein 7 by serpin mechanism."

[7].
"Preliminary report: circulating levels of the adipokine vaspin in gestational diabetes mellitus and preeclampsia."

[8].
"Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score."

[9].
"Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study."

[10].
"Combined effects of body mass index and cardio/respiratory fitness on serum vaspin concentrations in Korean young men."
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