ABCA1 (基因名), Phospholipid-transporting ATPase ABCA1 (蛋白名), abca1_human.
产品名称:
Human ABCA1/ Phospholipid-transporting ATPase ABCA1 CLIA Kit
腺苷三磷酸结合盒转运蛋白A1
货号:
U1242h
商标:
EIAab®
监管等级:
别名:
ATP-binding cassette sub-family A member 1, ATP-binding cassette transporter 1, Cholesterol efflux regulatory protein, ABC-1, ABC1, CERP
检测方法:
CLIA
实验类型:
Sandwich
检测范围:
19.5-1250pg/mL
特异性:
Natural and recombinant human Phospholipid-transporting ATPase ABCA1
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
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研究领域:
Cardiovascular
通用注释
亚单元:
Interacts with MEGF10 (PubMed:17205124). May interact with APOE1; functionally associated with APOE1 in the biogenesis of HDLs (PubMed:14754908).
功能:
Catalyzes the translocation of specific phospholipids from the cytoplasmic to the extracellular/lumenal leaflet of membrane coupled to the hydrolysis of ATP (PubMed:24097981). Thereby, participates to phospholipids transfer to apoliproteins to form nascent high density lipoproteins/HDLs (PubMed:14754908). Transports preferentially phosphatidylcholine over phosphatidylserine (PubMed:24097981). May involved indirectly in the efflux of intracellular cholesterol and its transfer to apoliproteins to form nascent high density lipoproteins/HDLs (PubMed:10533863, PubMed:14754908, PubMed:24097981).
亚细胞位置:
Membrane
Multi-pass membrane protein
Cell membrane
Endosome
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