Acer2 (基因名), Alkaline ceramidase 2 (蛋白名), acer2_mouse.
产品名称:
Mouse Acer2/ Alkaline ceramidase 2 CLIA Kit
货号:
U11204m
商标:
EIAab®
监管等级:
别名:
Acylsphingosine deacylase 3-like, Cancer-related gene liver 1 protein, N-acylsphingosine amidohydrolase 3-like, CRG-L1, AlkCDase 2, Asah3l
检测方法:
CLIA
特异性:
Natural and recombinant mouse Alkaline ceramidase 2
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
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研究领域:
-
通用注释
亚单元:
N/A
功能:
Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. Unsaturated long-chain ceramides are the best substrates, saturated long-chain ceramides and unsaturated very long-chain ceramides are good substrates, whereas saturated very long-chain ceramides and short-chain ceramides were poor substrates. Inhibits the maturation of protein glycosylation in the Golgi complex, including that of integrin beta-1 (ITGB1) and of LAMP1, by increasing the levels of sphingosine. Inhibits cell adhesion by reducing the level of ITGB1 in the cell surface. May have a role in cell proliferation and apoptosis that seems to depend on the balance between sphingosine and sphingosine-1-phosphate.
亚细胞位置:
Golgi apparatus membrane
Multi-pass membrane protein
数据库链接
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