ACMSD (基因名), 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase (蛋白名), acmsd_human.
产品名称:
Human ACMSD/ 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase CLIA Kit
2-amino-3-carboxymuconate-6-semialdehyde脱羧酶
货号:
U15399h
商标:
EIAab®
监管等级:
别名:
Picolinate carboxylase
检测方法:
CLIA
特异性:
Natural and recombinant human 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
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研究领域:
-
通用注释
亚单元:
Monomer.
功能:
Converts alpha-amino-beta-carboxymuconate-epsilon-semialdehyde (ACMS) to alpha-aminomuconate semialdehyde (AMS). ACMS can be converted non-enzymatically to quinolate (QA), a key precursor of NAD, and a potent endogenous excitotoxin of neuronal cells which is implicated in the pathogenesis of various neurodegenerative disorders. In the presence of ACMSD, ACMS is converted to AMS, a benign catabolite. ACMSD ultimately controls the metabolic fate of tryptophan catabolism along the kynurenine pathway.
亚细胞位置:
N/A
数据库链接
UniGene:
SMR:
STRING:
KEGG:
MIM:
Pfam:
Uniprot:
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