Rat Acsl3/ Long-chain-fatty-acid--CoA ligase 3 CLIA Kit

货号:

U10441r

商标:

EIAab^®

监管等级:

RUO

别名:

Arachidonate--CoA ligase, Brain acyl-CoA synthetase II, Long-chain acyl-CoA synthetase 3, LACS 3, Acs3, Facl3

检测方法:

CLIA

特异性:

Natural and recombinant rat Long-chain-fatty-acid--CoA ligase 3

样品类型:

Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids

样品数据:

研究领域:

Cardiovascular

规格 & 价格:

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Rat Acsl3 CLIA Kit

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通用注释

亚单元:

N/A

功能:

Catalyzes the conversion of long-chain fatty acids to their active form acyl-CoA for both synthesis of cellular lipids, and degradation via beta-oxidation (PubMed:28209804, PubMed:19737935, PubMed:15683247). ACSL3 is required for the incorporation of fatty acids into phosphatidylcholine, the major phospholipid located on the surface of VLDL (very low density lipoproteins) (By similarity). Has mainly an anabolic role in energy metabolism. Mediates hepatic lipogenesis (PubMed:19737935). Preferentially uses myristate, laurate, arachidonate and eicosapentaenoate as substrates (PubMed:9276691, PubMed:8663269). Both isoforms exhibit the same level of activity (PubMed:9276691).

亚细胞位置:

Mitochondrion outer membrane Single-pass type III membrane protein Peroxisome membrane Single-pass type III membrane protein Microsome membrane Single-pass type III membrane protein Endoplasmic reticulum membrane Single-pass type III membrane protein

数据库链接

UniGene:

Rn.54820

STRING:

10116.ENSRNOP00000020161

KEGG:

rno:114024

Pfam:

PF00501

Uniprot:

Q63151

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