ACSL5 (基因名), Long-chain-fatty-acid--CoA ligase 5 (蛋白名), acsl5_human.
产品名称:
Human ACSL5/ Long-chain-fatty-acid--CoA ligase 5 CLIA Kit
货号:
U10443h
商标:
EIAab®
监管等级:
别名:
Arachidonate--CoA ligase, Long-chain acyl-CoA synthetase 5, LACS 5, UNQ633/PRO1250, ACS5, FACL5
检测方法:
CLIA
特异性:
Natural and recombinant human Long-chain-fatty-acid--CoA ligase 5
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
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研究领域:
-
通用注释
亚单元:
N/A
功能:
Catalyzes the conversion of long-chain fatty acids to their active form acyl-CoAs for both synthesis of cellular lipids, and degradation via beta-oxidation (PubMed:17681178, PubMed:24269233, PubMed:22633490). ACSL5 may activate fatty acids from exogenous sources for the synthesis of triacylglycerol destined for intracellular storage (By similarity). Utilizes a wide range of saturated fatty acids with a preference for C16-C18 unsaturated fatty acids (By similarity). It was suggested that it may also stimulate fatty acid oxidation (By similarity). At the villus tip of the crypt-villus axis of the small intestine may sensitize epithelial cells to apoptosis specifically triggered by the death ligand TRAIL. May have a role in the survival of glioma cells.
亚细胞位置:
Mitochondrion
Endoplasmic reticulum
Mitochondrion outer membrane
Single-pass type III membrane protein
Endoplasmic reticulum membrane
Single-pass type III membrane protein
Cell membrane
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