ADAM22 (基因名), Disintegrin and metalloproteinase domain-containing protein 22 (蛋白名), ada22_human.
产品名称:
Human ADAM22/ Disintegrin and metalloproteinase domain-containing protein 22 CLIA Kit
货号:
U14575h
商标:
EIAab®
监管等级:
别名:
Metalloproteinase-disintegrin ADAM22-3, Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 2, ADAM 22, MDC2
检测方法:
CLIA
特异性:
Natural and recombinant human Disintegrin and metalloproteinase domain-containing protein 22
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
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研究领域:
-
通用注释
亚单元:
Interacts with LGI1 and can bind to LGI4 (By similarity). Interacts with KCNA2, DLG2 and DLG4 (By similarity). Interacts through its C-terminal region with YWHAB/14-3-3 beta and YWHAZ/14-3-3 zeta but not with YWHAE/14-3-3 epsilon or YWHAH/14-3-3 eta.
功能:
Probable ligand for integrin in the brain. This is a non catalytic metalloprotease-like protein (PubMed:19692335). Involved in regulation of cell adhesion and spreading and in inhibition of cell proliferation. Neuronal receptor for LGI1.
亚细胞位置:
Membrane
Single-pass type I membrane protein
Cell projection
Axon
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