Bovine AGO3/ Protein argonaute-3 CLIA Kit

货号:

U11450b

商标:

EIAab^®

监管等级:

RUO

别名:

Argonaute RISC catalytic component 3, Eukaryotic translation initiation factor 2C 3, eIF-2C 3, 3.1.26.n2, Argonaute3, EIF2C3

检测方法:

CLIA

特异性:

Natural and recombinant bovine Protein argonaute-3

样品类型:

Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids

样品数据:

研究领域:

规格 & 价格:

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Bovine AGO3 CLIA Kit

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数据
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通用注释

亚单元:

Interacts with EIF4B, IMP8, PRMT5 and TNRC6B (By similarity). Interacts with APOBEC3F, APOBEC3G and APOBEC3H. Interacts with EDC4 (By similarity).

功能:

Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Proposed to be involved in stabilization of small RNA derivates (riRNA) derived from processed RNA polymerase III-transcribed Alu repeats containing a DR2 retinoic acid response element (RARE) in stem cells and in the subsequent riRNA-dependent degradation of a subset of RNA polymerase II-transcribed coding mRNAs by recruiting a mRNA decapping complex involving EDC4. Possesses RNA slicer activity but only on select RNAs bearing 5'- and 3'-flanking sequences to the region of guide-target complementarity (By similarity).

亚细胞位置:

Cytoplasm P-body

数据库链接

UniGene:

Bt.47704

SMR:

Q6T5B7

STRING:

9913.ENSBTAP00000024385

KEGG:

bta:406231

Pfam: