Ahi1 (基因名), Jouberin (蛋白名), ahi1_rat.
产品名称:
Rat Ahi1/ Jouberin CLIA Kit
Jouberin
货号:
U2445r
商标:
EIAab®
监管等级:
别名:
Abelson helper integration site 1 protein homolog, AHI-1
检测方法:
CLIA
特异性:
Natural and recombinant rat Jouberin
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
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研究领域:
Cancer
通用注释
亚单元:
Self-associates. Part of the tectonic-like complex (also named B9 complex). Interacts with MKS1. Interacts with NPHP1; probably as heterodimers and/or AHI1(2):NPHP1(2) heterotetramers. Interacts (via SH3 domain) with the dynamin GTPase DNM2. Interacts with HAP1; probably as AHI1(2):HAP1(2) heterotetramers. Interacts with RAB8A. Interacts with CEND1.
功能:
Involved in vesicle trafficking and required for ciliogenesis, formation of primary non-motile cilium, and recruitment of RAB8A to the basal body of primary cilium. Component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes. Involved in neuronal differentiation.
亚细胞位置:
Cytoplasm
Cytoskeleton
Cilium basal body
Cytoplasm
Cytoskeleton
Microtubule organizing center
Centrosome
Centriole
Cell junction
Adherens junction
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