Akap1 (基因名), A-kinase anchor protein 1, mitochondrial (蛋白名), akap1_mouse.
产品名称:
Mouse Akap1/ A-kinase anchor protein 1, mitochondrial CLIA Kit
线粒体,a激酶锚定蛋白1
货号:
U15276m
商标:
EIAab®
监管等级:
别名:
Dual specificity A-kinase-anchoring protein 1, Protein kinase A-anchoring protein 1, Spermatid A-kinase anchor protein, D-AKAP-1, PRKA1, S-AKAP, Akap
检测方法:
CLIA
特异性:
Natural and recombinant mouse A-kinase anchor protein 1, mitochondrial
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
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研究领域:
-
通用注释
亚单元:
Interacts with SLC8A3.
功能:
Differentially targeted protein that binds to type I and II regulatory subunits of protein kinase A. Anchors them to the cytoplasmic face of the mitochondrial outer membrane or allows them to reside in the endoplasmic reticulum. Does not contain the classic KDEL endoplasmic reticulum-targeting sequence. This explains how it is able to switch its localization, either being in the endoplasmic reticulum or in the mitochondria depending on which N-terminal part begins the isoform. The longest N-terminal part only present in isoform 2 and isoform 4 acts as a suppressor of mitochondrial targeting and as an activator of recessive endoplasmic reticulum targeting motif.
亚细胞位置:
Isoform 6
Mitochondrion outer membrane
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