Akap9 (基因名), A-kinase anchor protein 9 (蛋白名), akap9_mouse.
产品名称:
Mouse Akap9/ A-kinase anchor protein 9 CLIA Kit
货号:
U11363m
商标:
EIAab®
监管等级:
别名:
Protein kinase A-anchoring protein 9, PRKA9, AKAP-9, Kiaa0803
检测方法:
CLIA
特异性:
Natural and recombinant mouse A-kinase anchor protein 9
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
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研究领域:
-
通用注释
亚单元:
Interacts with the regulatory region of protein kinase N (PKN), protein phosphatase 2A (PP2A), protein phosphatase 1 (PP1) and the immature non-phosphorylated form of PKC epsilon. Interacts with CIP4 and FNBP1. Interacts with chloride intracellular channel proteins CLIC1, CLIC4 and CLIC5. CSNK1D binding promotes its centrosomal subcellular location. Interacts with GM130/GOLGA2; leading to recruitment to the Golgi apparatus. Interacts with KCNQ1; targets protein kinase A (PKA) catalytic and regulatory subunits and protein phosphatase 1 (PP1), to the heterodimer KCNQ1-KCNE1.
功能:
Scaffolding protein that assembles several protein kinases and phosphatases on the centrosome and Golgi apparatus. Required to maintain the integrity of the Golgi apparatus. Recruited to the Golgi apparatus by GM130/GOLGA2 and is required for microtubule nucleation at the cis-side of the Golgi apparatusGM130/GOLGA2.
亚细胞位置:
Cytoplasm
Cytoplasm
Cytoskeleton
Microtubule organizing center
Centrosome
Golgi apparatus
Cytoplasmic in parietal cells.
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