Apba1 (基因名), Amyloid-beta A4 precursor protein-binding family A member 1 (蛋白名), apba1_rat.
产品名称:
Rat Apba1/ Amyloid-beta A4 precursor protein-binding family A member 1 CLIA Kit
淀粉样βA4前体蛋白结合家族A成员1
货号:
U10313r
商标:
EIAab®
监管等级:
别名:
Adapter protein X11alpha, Neuron-specific X11 protein, Neuronal Munc18-1-interacting protein 1, Mint-1, Mint1, X11
检测方法:
CLIA
特异性:
Natural and recombinant rat Amyloid-beta A4 precursor protein-binding family A member 1
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
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研究领域:
-
通用注释
亚单元:
Part of a multimeric complex containing Munc18-1 and syntaxin-1. Also part of the brain-specific heterotrimeric complex LIN-10/X11-alpha, LIN-2/CASK, and LIN7. Binds to the cytoplasmic domain of amyloid protein (APP) (By similarity). Interacts (via PDZ 1 and 2 domains) with FSPB (By similarity). Isoform 2 interacts (via its truncated PID domain) with active, GTP-bound RAB6A and RAB6B (By similarity).
功能:
Putative function in synaptic vesicle exocytosis by binding to Munc18-1, an essential component of the synaptic vesicle exocytotic machinery. May modulate processing of the amyloid-beta precursor protein (APP) and hence formation of APP-beta.
亚细胞位置:
Isoform 2
Golgi apparatus
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