APOC3 (基因名), Apolipoprotein C-III (蛋白名), apoc3_human.
产品名称:
Human APOC3/ Apolipoprotein C-III CLIA Kit
载脂蛋白C3
货号:
U1890h
商标:
EIAab®
监管等级:
别名:
Apolipoprotein C3, Apo-CIII
检测方法:
CLIA
实验类型:
Sandwich
检测范围:
0.312-20ng/mL
特异性:
Natural and recombinant human Apolipoprotein C-III
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
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研究领域:
Metabolism
通用注释
亚单元:
N/A
功能:
Component of triglyceride-rich very low density lipoproteins (VLDL) and high density lipoproteins (HDL) in plasma (PubMed:18201179, PubMed:22510806). Plays a multifaceted role in triglyceride homeostasis (PubMed:18201179, PubMed:22510806). Intracellularly, promotes hepatic very low density lipoprotein 1 (VLDL1) assembly and secretion; extracellularly, attenuates hydrolysis and clearance of triglyceride-rich lipoproteins (TRLs) (PubMed:18201179, PubMed:22510806). Impairs the lipolysis of TRLs by inhibiting lipoprotein lipase and the hepatic uptake of TRLs by remnant receptors (PubMed:18201179, PubMed:22510806). Formed of several curved helices connected via semiflexible hinges, so that it can wrap tightly around the curved micelle surface and easily adapt to the different diameters of its natural binding partners (PubMed:18408013).
亚细胞位置:
Secreted
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