Pig ATG5/ Autophagy protein 5 CLIA Kit
自噬蛋白5

货号:

U15032p

商标:

EIAab^®

监管等级:

RUO

检测方法:

CLIA

实验类型:

Sandwich

特异性:

Natural and recombinant pig Autophagy protein 5

样品类型:

Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids

样品数据:

研究领域:

Cancer

规格 & 价格:

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Pig ATG5 CLIA Kit

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产品说明书

说明书:

MSDS:

在线询价

数据
文献
序列 / 3D
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通用注释

亚单元:

Forms a conjugate with ATG12. The ATG5-ATG12 conjugate forms a complex with several units of ATG16L. Interacts with TECPR1; the interaction is direct and does not take place when ATG16 is associated with the ATG5-ATG12 conjugate (By similarity). ATG12-ATG5 also interacts with MAVS, MGA, and RARRES3 (By similarity). Interacts with ATG3, ATG7 and ATG10. Interacts with FADD.

功能:

May play an important role in the apoptotic process, possibly within the modified cytoskeleton. Its expression is a relatively late event in the apoptotic process, occurring downstream of caspase activity. Plays a crucial role in IFN-gamma-induced autophagic cell death by interacting with FADD.

亚细胞位置:

Cytoplasm Preautophagosomal structure membrane Peripheral membrane protein The conjugate detaches from the membrane immediately before or after autophagosome formation is completed. Localizes also to discrete punctae along the ciliary axoneme and to the base of the ciliary axoneme.

数据库链接

UniGene:

Ssc.83739

SMR:

Q3MQ04

KEGG:

ssc:641362

Pfam:

PF04106

Uniprot:

Q3MQ04

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