Bace2 (基因名), Beta-secretase 2 (蛋白名), bace2_rat.
产品名称:
Rat Bace2/ Beta-secretase 2 CLIA Kit
β分泌酶2
货号:
U1812r
商标:
EIAab®
监管等级:
别名:
Beta-site amyloid precursor protein cleaving enzyme 2, Memapsin-1, Membrane-associated aspartic protease 1, Theta-secretase, Beta-site APP cleaving enzyme 2
检测方法:
CLIA
特异性:
Natural and recombinant rat Beta-secretase 2
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
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研究领域:
Neurosciences
通用注释
亚单元:
Monomer. Interacts ith RTN3 and RTN4.
功能:
Responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves APP, between residues 690 and 691, leading to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase. It has also been shown that it can cleave APP between residues 671 and 672.
亚细胞位置:
Membrane
Single-pass type I membrane protein
Golgi apparatus
Endoplasmic reticulum
Endosome
Cell surface
数据库链接
UniGene:
SMR:
STRING:
KEGG:
Pfam:
Uniprot:
验证序列:
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