Baiap2 (基因名), Brain-specific angiogenesis inhibitor 1-associated protein 2 (蛋白名), baip2_rat.
产品名称:
Rat Baiap2/ Brain-specific angiogenesis inhibitor 1-associated protein 2 CLIA Kit
货号:
U14118r
商标:
EIAab®
监管等级:
别名:
Insulin receptor substrate protein of 53 kDa, Insulin receptor tyrosine kinase substrate protein p53, IRSp53, BAI-associated protein 2
检测方法:
CLIA
特异性:
Natural and recombinant rat Brain-specific angiogenesis inhibitor 1-associated protein 2
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
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研究领域:
-
通用注释
亚单元:
Homodimer. Interacts with CDC42 and RAC1 that have been activated by GTP binding. Binds TIAM1. Interacts with ATN1, BAI1, DIAPH1, EPS8, SHANK1, SHANK2, SHANK3, WASF1 and WASF2. Interacts with ENAH after recruitment of CDC42.
功能:
Adapter protein that links membrane-bound small G-proteins to cytoplasmic effector proteins. Necessary for CDC42-mediated reorganization of the actin cytoskeleton and for RAC1-mediated membrane ruffling. Involved in the regulation of the actin cytoskeleton by WASF family members and the Arp2/3 complex. Plays a role in neurite growth. Acts syngeristically with ENAH to promote filipodia formation. Plays a role in the reorganization of the actin cytoskeleton in response to bacterial infection. Participates in actin bundling when associated with EPS8, promoting filopodial protrusions.
亚细胞位置:
Cytoplasm
Membrane
Peripheral membrane protein
Cell projection
Filopodium
Cell projection
Ruffle
Cytoplasm
Cytoskeleton
Detected throughout the cytoplasm in the absence of specific binding partners. Detected in filopodia and close to membrane ruffles. Recruited to actin pedestals that are formed upon infection by bacteria at bacterial attachment sites (By similarity).
数据库链接
UniGene:
SMR:
STRING:
KEGG:
Pfam:
Uniprot:
验证序列:
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