Bmp2 (基因名), Bone morphogenetic protein 2 (蛋白名), bmp2_rat.
产品名称:
Rat Bmp2/ Bone morphogenetic protein 2 CLIA Kit
骨成型蛋白2
货号:
U0013r
商标:
EIAab®
监管等级:
别名:
Bone morphogenetic protein 2A, BMP-2A, BMP-2, Bmp-2
检测方法:
CLIA
实验类型:
Sandwich
检测范围:
7.8-500pg/mL
特异性:
Natural and recombinant rat Bone morphogenetic protein 2
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
登录.
研究领域:
Cancer
通用注释
亚单元:
Homodimer; disulfide-linked. Interacts with SOSTDC1 and GREM2. Interacts with ASPN. Interacts with MFAP5. Interacts with FBN1 (via N-terminal domain) and FBN2.
功能:
Induces cartilage and bone formation. Stimulates the differentiation of myoblasts into osteoblasts via the EIF2AK3-EIF2A-ATF4 pathway. BMP2 activation of EIF2AK3 stimulates phosphorylation of EIF2A which leads to increased expression of ATF4 which plays a central role in osteoblast differentiation. In addition stimulates TMEM119, which upregulates the expression of ATF4.
亚细胞位置:
Secreted
数据库链接
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