Human BMP4/ Bone morphogenetic protein 4 CLIA Kit
骨形成蛋白4

货号:

U0014h

商标:

EIAab^®

监管等级:

RUO

别名:

Bone morphogenetic protein 2B, BMP-2B, BMP-4, BMP2B, DVR4

检测方法:

CLIA

实验类型:

Sandwich

检测范围:

3.9-250pg/mL

特异性:

Natural and recombinant human Bone morphogenetic protein 4

样品类型:

Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids

样品数据:

研究领域:

Cancer

规格 & 价格:

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Human BMP4 CLIA Kit

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产品说明书

说明书:

MSDS:

在线询价

数据
文献
序列 / 3D
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通用注释

亚单元:

Homodimer; disulfide-linked (By similarity). Interacts with GREM2. Part of a complex consisting of TWSG1 and CHRD. Interacts with the serine proteases, HTRA1 and HTRA3; the interaction with either inhibits BMP4-mediated signaling. The HTRA protease activity is required for this inhibition (By similarity). Interacts with SOSTDC1. Interacts with FBN1 (via N-terminal domain) and FBN2 (PubMed:18339631).

功能:

Induces cartilage and bone formation. Also act in mesoderm induction, tooth development, limb formation and fracture repair. Acts in concert with PTHLH/PTHRP to stimulate ductal outgrowth during embryonic mammary development and to inhibit hair follicle induction.

亚细胞位置:

Secreted Extracellular space Extracellular matrix

数据库链接

UniGene:

Hs.68879

STRING:

9606.ENSP00000245451

KEGG:

hsa:652

MIM:

112262

Pfam: