Human BMPR1A/ Bone morphogenetic protein receptor type-1A CLIA Kit
骨成型蛋白受体1A

货号:

U0015h

商标:

EIAab^®

监管等级:

RUO

别名:

Activin receptor-like kinase 3, Serine/threonine-protein kinase receptor R5, ALK-3, SKR5, CD292, BMP type-1A receptor, ACVRLK3, ALK3

检测方法:

CLIA

实验类型:

Sandwich

检测范围:

39-2500pg/mL

特异性:

Natural and recombinant human Bone morphogenetic protein receptor type-1A

样品类型:

Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids

样品数据:

研究领域:

规格 & 价格:

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Human BMPR1A CLIA Kit

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产品说明书

说明书:

MSDS:

在线询价

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通用注释

亚单元:

Interacts with BMP2 (PubMed:10881198, PubMed:18937504). Interacts with low affinity with GDF5; positively regulates chondrocyte differentiation (PubMed:24098149).

功能:

On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for BMP2, BMP4, GDF5 and GDF6. Positively regulates chondrocyte differentiation through GDF5 interaction. Mediates induction of adipogenesis by GDF6.

亚细胞位置:

Membrane Single-pass type I membrane protein

数据库链接

UniGene:

Hs.524477

SMR:

P36894

STRING:

9606.ENSP00000224764

KEGG:

hsa:657

MIM: