C1QA (基因名), Complement C1q subcomponent subunit A (蛋白名), c1qa_human.
产品名称:
Human C1QA/ Complement C1q subcomponent subunit A CLIA Kit
补体C1q亚基A
货号:
U0747h
商标:
EIAab®
监管等级:
检测方法:
CLIA
实验类型:
Sandwich
检测范围:
19.5-1250pg/mL
特异性:
Natural and recombinant human Complement C1q subcomponent subunit A
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
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研究领域:
Neurosciences
通用注释
亚单元:
C1 is a calcium-dependent trimolecular complex of C1q, R and S in the molar ration of 1:2:2. C1q subcomponent is composed of nine subunits, six of which are disulfide-linked dimers of the A and B chains, and three of which are disulfide-linked dimers of the C chain.
功能:
C1q associates with the proenzymes C1r and C1s to yield C1, the first component of the serum complement system. The collagen-like regions of C1q interact with the Ca(2+)-dependent C1r(2)C1s(2) proenzyme complex, and efficient activation of C1 takes place on interaction of the globular heads of C1q with the Fc regions of IgG or IgM antibody present in immune complexes.
亚细胞位置:
Secreted
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