C1qc (基因名), Complement C1q subcomponent subunit C (蛋白名), c1qc_rat.
产品名称:
Rat C1qc/ Complement C1q subcomponent subunit C CLIA Kit
补体C1q子成分C亚基
货号:
U0339r
商标:
EIAab®
监管等级:
别名:
C1qg
检测方法:
CLIA
特异性:
Natural and recombinant rat Complement C1q subcomponent subunit C
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
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研究领域:
Neurosciences
通用注释
亚单元:
C1 is a calcium-dependent trimolecular complex of C1q, C1r and C1s in the molar ration of 1:2:2. C1q subcomponent is composed of nine subunits, six of which are disulfide-linked dimers of the a and B chains, and three of which are disulfide-linked dimers of the C chain. In addition to the major A:B and C:C dimer bands, rat, unlike human C1q, contained minor dimer species.
功能:
C1q associates with the proenzymes C1r and C1s to yield C1, the first component of the serum complement system. The collagen-like regions of C1q interact with the Ca(2+)-dependent C1r(2)C1s(2) proenzyme complex, and efficient activation of C1 takes place on interaction of the globular heads of C1q with the Fc regions of IgG or IgM antibody present in immune complexes.
亚细胞位置:
Secreted
数据库链接
UniGene:
SMR:
STRING:
KEGG:
Pfam:
Uniprot:
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