CALD1 (基因名), Caldesmon (蛋白名), cald1_chick.
通用注释
亚单元:
N/A
功能:
Actin- and myosin-binding protein implicated in the regulation of actomyosin interactions in smooth muscle and nonmuscle cells (could act as a bridge between myosin and actin filaments). Stimulates actin binding of tropomyosin which increases the stabilization of actin filament structure. In muscle tissues, inhibits the actomyosin ATPase by binding to F-actin. This inhibition is attenuated by calcium-calmodulin and is potentiated by tropomyosin. Interacts with actin, myosin, two molecules of tropomyosin and with calmodulin. Also play an essential role during cellular mitosis and receptor capping.
亚细胞位置:
Cytoplasm
Cytoskeleton
Cytoplasm
Myofibril
On thin filaments in smooth muscle and on stress fibers in fibroblasts (nonmuscle).
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