CAPN2 (基因名), Calpain-2 catalytic subunit (蛋白名), can2_pig.
产品名称:
Pig CAPN2/ Calpain-2 catalytic subunit CLIA Kit
Calpain-2催化亚基
货号:
U2249p
商标:
EIAab®
监管等级:
别名:
Calcium-activated neutral proteinase 2, Calpain M-type, Calpain-2 large subunit, Millimolar-calpain, CANP 2, M-calpain
检测方法:
CLIA
实验类型:
Sandwich
特异性:
Natural and recombinant pig Calpain-2 catalytic subunit
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
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研究领域:
Neurosciences
通用注释
亚单元:
Forms a heterodimer with a small (regulatory) subunit (CAPNS1). Interacts with CPEB3; this leads to cleavage of CPEB3.
功能:
Calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction. Proteolytically cleaves MYOC at 'Arg-226'. Proteolytically cleaves CPEB3 following neuronal stimulation which abolishes CPEB3 translational repressor activity, leading to translation of CPEB3 target mRNAs.
亚细胞位置:
Cytoplasm
Cell membrane
Translocates to the plasma membrane upon Ca(2+) binding.
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