Rat Capn2/ Calpain-2 catalytic subunit CLIA Kit
Calpain-2催化亚基

货号:

U2249r

商标:

EIAab^®

监管等级:

RUO

别名:

Calcium-activated neutral proteinase 2, Calpain M-type, Calpain-2 large subunit, Millimolar-calpain, CANP 2, M-calpain

检测方法:

CLIA

实验类型:

Sandwich

检测范围:

39-2500pg/mL

特异性:

Natural and recombinant rat Calpain-2 catalytic subunit

样品类型:

Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids

样品数据:

研究领域:

Neurosciences

规格 & 价格:

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Rat Capn2 CLIA Kit

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产品说明书

说明书:

MSDS:

在线询价

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通用注释

亚单元:

Forms a heterodimer with a small (regulatory) subunit (CAPNS1) (PubMed:19020622, PubMed:19020623). Interacts with CPEB3; this leads to cleavage of CPEB3.

功能:

Calcium-regulated non-lysosomal thiol-protease which catalyze limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction. Proteolytically cleaves MYOC at 'Arg-226'. Proteolytically cleaves CPEB3 following neuronal stimulation which abolishes CPEB3 translational repressor activity, leading to translation of CPEB3 target mRNAs.

亚细胞位置:

Cytoplasm Cell membrane Translocates to the plasma membrane upon Ca(2+) binding.

数据库链接

UniGene:

Rn.6822

SMR:

Q07009

STRING:

10116.ENSRNOP00000046509

KEGG:

rno:29154

Pfam: