CAPZB (基因名), F-actin-capping protein subunit beta isoforms 1 and 2 (蛋白名), capzb_chick.
产品名称:
Chicken CAPZB/ F-actin-capping protein subunit beta isoforms 1 and 2 CLIA Kit
货号:
U16100c
商标:
EIAab®
监管等级:
别名:
Beta-actinin subunit II, CapZ 36/32, CapZ B1 and B2
检测方法:
CLIA
特异性:
Natural and recombinant chicken F-actin-capping protein subunit beta isoforms 1 and 2
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
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研究领域:
-
通用注释
亚单元:
Heterodimer of an alpha and a beta subunit. Component of the WASH complex (By similarity). Isoform 2 also is a component of dynactin complex from brain, which contains the actin-related protein ARP1.
功能:
F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. May play a role in the regulation of cell morphology and cytoskeletal organization.
亚细胞位置:
Isoform 2
Cytoplasm
Myofibril
Sarcomere
I band
Cytoplasm
Cytoskeleton
In cardiac muscle, isoform 2 is located at sarcomere intercalated disks.
数据库链接
UniGene:
SMR:
STRING:
KEGG:
Pfam:
Uniprot:
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