Human CHI3L1/ Chitinase-3-like protein 1 CLIA Kit
软骨糖蛋白39

货号:

U1463h

商标:

EIAab^®

监管等级:

RUO

别名:

39 kDa synovial protein, Cartilage glycoprotein 39, YKL-40, CGP-39

检测方法:

CLIA

实验类型:

Sandwich

检测范围:

3.9-250pg/mL

特异性:

Natural and recombinant human Chitinase-3-like protein 1

样品类型:

Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids

样品数据:

研究领域:

Signal Transduction

规格 & 价格:

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Human CHI3L1 CLIA Kit

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产品说明书

说明书:

MSDS:

在线询价

数据
文献
序列 / 3D
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通用注释

亚单元:

Monomer.

功能:

Carbohydrate-binding lectin with a preference for chitin. Has no chitinase activity. May play a role in tissue remodeling and in the capacity of cells to respond to and cope with changes in their environment. Plays a role in T-helper cell type 2 (Th2) inflammatory response and IL-13-induced inflammation, regulating allergen sensitization, inflammatory cell apoptosis, dendritic cell accumulation and M2 macrophage differentiation. Facilitates invasion of pathogenic enteric bacteria into colonic mucosa and lymphoid organs. Mediates activation of AKT1 signaling pathway and subsequent IL8 production in colonic epithelial cells. Regulates antibacterial responses in lung by contributing to macrophage bacterial killing, controlling bacterial dissemination and augmenting host tolerance. Also regulates hyperoxia-induced injury, inflammation and epithelial apoptosis in lung.

亚细胞位置:

Secreted Extracellular space Cytoplasm Cytoplasm Perinuclear region Endoplasmic reticulum

数据库链接

UniGene:

Hs.382202

SMR:

P36222

STRING:

9606.ENSP00000255409

KEGG:

hsa:1116

MIM: