Human C2/ Complement C2 CLIA Kit
补充C2

货号:

U1794h

商标:

EIAab^®

监管等级:

RUO

别名:

C3/C5 convertase

检测方法:

CLIA

实验类型:

Sandwich

检测范围:

1.95-125ng/mL

特异性:

Natural and recombinant human Complement C2

样品类型:

Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids

样品数据:

研究领域:

Immunology

规格 & 价格:

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Human C2 CLIA Kit

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产品说明书

说明书:

MSDS:

在线询价

数据
文献
序列 / 3D
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通用注释

亚单元:

C2a interacts with Schistosoma haematobium TOR (via N-terminal extracellular domain). This results in inhibition of the classical and lectin pathway of complement activation, probably due to interference with binding of C2a to C4b such that C3 convertase cannot be formed. This infers resistance to complement-mediated cell lysis, allowing parasite survival and infection.

功能:

Component C2 which is part of the classical pathway of the complement system is cleaved by activated factor C1 into two fragments: C2b and C2a. C2a, a serine protease, then combines with complement factor C4b to generate the C3 or C5 convertase.

亚细胞位置:

Secreted

数据库链接

UniGene:

Hs.408903

SMR:

P06681

STRING:

9606.ENSP00000299367

KEGG:

hsa:717

MIM: