MT-CO1 (基因名), Cytochrome c oxidase subunit 1 (蛋白名), cox1_human.
产品名称:
Human MT-CO1/ Cytochrome c oxidase subunit 1 CLIA Kit
细胞色素C氧化酶亚基1
货号:
U8727h
商标:
EIAab®
监管等级:
别名:
Cytochrome c oxidase polypeptide I, COI, COXI, MTCO1
检测方法:
CLIA
实验类型:
Sandwich
检测范围:
39-2500pg/mL
特异性:
Natural and recombinant human Cytochrome c oxidase subunit 1
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
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研究领域:
-
通用注释
亚单元:
As a newly synthesized protein, rapidly incorporates into a multi-subunit assembly intermediate in the inner membrane, called MITRAC (mitochondrial translation regulation assembly intermediate of cytochrome c oxidase) complex, whose core components are COA3/MITRAC12 and COX14. Within the MITRAC complex, interacts with COA3 and with SMIM20/MITRAC7; the interaction with SMIM20 stabilizes the newly synthesized MT-CO1 and prevents its premature turnover.
功能:
Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
亚细胞位置:
Mitochondrion inner membrane
Multi-pass membrane protein
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