DAD1 (基因名), Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1 (蛋白名), dad1_pig.
产品名称:
Pig DAD1/ Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1 CLIA Kit
货号:
U15753p
商标:
EIAab®
监管等级:
别名:
Defender against cell death 1, DAD-1, Oligosaccharyl transferase subunit DAD1
检测方法:
CLIA
特异性:
Natural and recombinant pig Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
登录.
研究领域:
Cancer
通用注释
亚单元:
Component of the oligosaccharyltransferase (OST) complex. OST exists in two different complex forms which contain common core subunits RPN1, RPN2, OST48, OST4, DAD1 and TMEM258, either STT3A or STT3B as catalytic subunits, and form-specific accessory subunits. OST can form stable complexes with the Sec61 complex or with both the Sec61 and TRAP complexes.
功能:
Essential subunit of the N-oligosaccharyl transferase (OST) complex which catalyzes the transfer of a high mannose oligosaccharide from a lipid-linked oligosaccharide donor to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains. Required for the assembly of both SST3A- and SS3B-containing OST complexes. Required for efficient N-glycosylation. Loss of the DAD1 protein triggers apoptosis.
亚细胞位置:
Endoplasmic reticulum membrane
Multi-pass membrane protein
数据库链接
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