RNASE3 (基因名), Eosinophil cationic protein (蛋白名), ecp_human.
产品名称:
Human RNASE3/ Eosinophil cationic protein CLIA Kit
嗜酸性粒细胞阳离子蛋白
货号:
U1758h
商标:
EIAab®
监管等级:
别名:
Ribonuclease 3, RNase 3, ECP, ECP, RNS3
检测方法:
CLIA
实验类型:
Sandwich
检测范围:
0.078-5ng/mL
特异性:
Natural and recombinant human Eosinophil cationic protein
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
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研究领域:
-
通用注释
亚单元:
Interacts with bacterial lipopolysaccharide (LPS) and lipoteichoic acid (LTA). In vitro interacts with and insert into lipid bilayers composed of dioleoyl phosphatidylcholine and dioleoyl phosphatidylglycerol. In vitro, tends to form amyloid-like aggregates at pH 3, but not at pH 5, nor 7.
功能:
Cytotoxin and helminthotoxin with low-efficiency ribonuclease activity. Possesses a wide variety of biological activities. Exhibits antibacterial activity, including cytoplasmic membrane depolarization of preferentially Gram-negative, but also Gram-positive strains. Promotes E.coli outer membrane detachment, alteration of the overall cell shape and partial loss of cell content.
亚细胞位置:
Secreted
Located in the matrix of eosinophil large specific granule, which are released following activation by an immune stimulus.
[3].
G Cangiano, E Proietti, MN Kronig, et al.
[4].
K Górska, M Paplińska-Goryca, P Nejman-Gryz, et al.
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