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ENPP2 (基因名), Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 (蛋白名), enpp2_human.

产品名称:

Human ENPP2/ Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 CLIA Kit
E-NPP2

货号:

U1228h

商标:

EIAab^®

监管等级:

RUO

别名:

Autotaxin, Extracellular lysophospholipase D, LysoPLD, E-NPP 2, ATX, PDNP2

检测方法:

CLIA

实验类型:

Sandwich

检测范围:

0.156-10ng/mL

特异性:

Natural and recombinant human Ectonucleotide pyrophosphatase/phosphodiesterase family member 2

样品类型:

Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids

样品数据:

研究领域:

Cardiovascular

规格 & 价格:

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产品说明书

说明书:

MSDS:

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通用注释

亚单元:

N/A

功能:

Hydrolyzes lysophospholipids to produce lysophosphatidic acid (LPA) in extracellular fluids. Major substrate is lysophosphatidylcholine. Also can act on sphingosylphosphphorylcholine producing sphingosine-1-phosphate, a modulator of cell motility. Can hydrolyze, in vitro, bis-pNPP, to some extent pNP-TMP, and barely ATP. Involved in several motility-related processes such as angiogenesis and neurite outgrowth. Acts as an angiogenic factor by stimulating migration of smooth muscle cells and microtubule formation. Stimulates migration of melanoma cells, probably via a pertussis toxin-sensitive G protein. May have a role in induction of parturition. Possible involvement in cell proliferation and adipose tissue development. Tumor cell motility-stimulating factor.

亚细胞位置:

Secreted Secreted by most body fluids including serum and CSF. Also by adipocytes and numerous cancer cells.

数据库链接

UniGene:

Hs.190977

SMR:

Q13822

KEGG:

hsa:5168

MIM:

601060

Pfam: